Biochem/physiol Actions

Cell permeable: no

Reversible: no

Target IC₅₀: 4 nM against cathepsin B

Primary Targetcathepsin B

Product does not compete with ATP.

General description

Note: this peptide forms cyclic isomers.

A more active lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC₅₀ = 4 nM) compared to leupeptin (IC₅₀ = 310 nM).

Lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC₅₀ = 4 nM) than of leupeptin (IC₅₀ = 310 nM). Note: this peptide forms cyclic isomers.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

McConnell, R.M., et al. 1993. J. Med. Chem. 36, 1084.

Packaging

1 mg in Plastic ampoule

Reconstitution

Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 1 month at -70°C.

Sequence

Ac-Leu-Val-lysinal

Warning

Toxicity: Standard Handling (A)